HIV Immunotherapy Treatment In Humans Shows Some Success

According to a study published in Nature, a new therapy using antibodies in HIV patients reduced the presence of the virus by up to 300 times. It is the first proof of concept that an antibody-based therapy could be effective in controlling HIV infection according to Barry Zingman, M.D., the Medical Director of the AIDS Center and Clinical Director of Infectious Diseases at Montefiore Medical Center Moses Division. The antibody treatment was injected in varying concentrations in 12 uninfected and… Read more

HIV NEWS: Stem Cell Therapy Clinical Trial Approved by FDA

San Francisco, California – An innovative therapy using a patient’s own stem cells, modified to resist infection with the AIDS virus, has been given approval by the Food and Drug Administration (FDA) to begin a clinical trial in people. CIRM, California’s stem cell agency, is funding that trial. The therapy focuses on a protein found on cells in the immune system. HIV hijacks this protein, using it to penetrate and infect our cells. Researchers at City of Hope near Los… Read more

New PrEP Study Shows 86% Effectiveness For Before/After Sex Dosing Schedule

For the first time, a study shows that a drug used to treat HIV infection also can help prevent it when taken before and after risky sex by gay men.

The results offer hope of a more appealing way to help prevent the disease beyond taking daily pills and using condoms, although those methods are still considered best.

The study, done in France and Canada, is the first to test “on demand” use of Truvada, a pill combining two AIDS drugs, by people planning to have risky sex. The uninfected men who took it were 86 percent less likely to get HIV compared to men given dummy pills.

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9 in 10 new U.S. HIV infections come from people not receiving HIV care

More than 90 percent of new HIV infections in the United States could be averted by diagnosing people living with HIV and ensuring they receive prompt, ongoing care and treatment. This finding was published today in JAMA Internal Medicine by researchers at the Centers for Disease Control and Prevention.

The analysis showed that 30 percent of new HIV infections were transmitted from people who did not know that they were infected with the virus, highlighting the importance of getting tested. People who had been diagnosed were less likely to transmit their infection, in part because people who know they have HIV are more likely to take steps to protect their partners from infection.

“Positive or negative, an HIV test opens the door to prevention. For someone who is positive, it can be the gateway to care and the signal to take steps to protect partners from infection. For someone who tests negative, it can be a direct link to important prevention services to help them stay HIV-free,” said Eugene McCray, MD, director of CDC’s Division of HIV/AIDS Prevention.

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amfAR Announces Strategy Aimed at Curing HIV

amfAR, The Foundation for AIDS Research, announced that it has created a $100 million investment strategy in support of its Countdown to a Cure for AIDS initiative, launched last year with the aim of developing the scientific basis of a cure by 2020. The establishment of the amfAR Institute for HIV Cure Research within a major academic research institution with a grant of $20 million will be the centerpiece of the investment strategy.

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Researcher Reports Two HIV Patients Showing No Signs of Virus

Dr. Timothy Henrich, a medical researcher with Harvard Medical School and Boston’s Brigham and Women’s Hospital, announced today that two of his HIV-positive patients showed no trace of the virus after receiving stem-cell transplants. His study and research was supported by amfAR, which issues a press release with additional information: Dr. Timothy Henrich of Harvard Medical School and Brigham and Women’s Hospital in Boston today reported on the case of two HIV-positive patients who show no trace of virus following… Read more

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